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. 2019 Apr 12;9:5971. doi: 10.1038/s41598-019-42564-5

Figure 2.

Figure 2

Dynamic Bayesian Network (DBN) analysis of circulating inflammatory mediators in PALF patients. Circulating inflammatory mediators in serum samples from PALF spontaneous survivors were segregated into three sub-groups (APAPo + NAC [n = 13 patients], non-APAPo + NAC [n = 8 patients], and non-APAPo non-NAC [n = 40 patients]) and non-survivors (n = 12 patients). DBN inference was performed as described in Materials and Methods. Inflammatory mediators are shown as nodes, and the arrows connecting them suggest an influence of one mediator on the one(s) to which it is connected. The arrows do not distinguish positive from negative influences of one mediator on another. Semi-circular arrows suggest either positive or negative feedback of a given mediator on itself. The thickness of each edge denotes the relative algorithmic confidence in a given interaction between nodes.