Table 2.

Correlation of clinical and laboratory variables with arylesterase activity in heart failure patients

Variables correlated to serum arylesterase activity		Non-diabetic patients with HF		Diabetic patients with HF
		Correlation coefficient	P-value	Correlation coefficient	P-value
Unadjusted	Age	−0.371	<0.001	−0.216	0.056
	Log HbA1c	0.035	0.699	0.068	0.554
	Total cholesterol	0.171	0.055	0.212	0.068
	HDL cholesterol	0.270	0.002	0.111	0.344
	ApoA-I	0.257	0.004	0.255	0.028
	eGFR	0.142	0.100	0.190	0.096
	Log NT-proBNP	−0.257	0.004	−0.353	0.003
	Log LVEF	0.098	0.254	0.303	0.007
	NYHA class	−0.301	<0.001	−0.474	<0.001
Adjusted*	Log NT-proBNP	−0.227	0.035	−0.313	0.025
	Log LVEF	0.089	0.415	0.325	0.020
	NYHA class	−0.451	<0.001	−0.554	<0.001

HF, heart failure; HbA1c, glycated hemoglobin A1c; eGFR, estimated glomerular filtration rate; hsCRP, high-sentivity C-reactive protein; NT-proBNP, N-terminal pro-B-type natriuretic peptide; LVEF, left ventricular ejection fraction.

*After adjustment for ages, sex, log transformed hsCRP, eGFR, apo A-I, history of smoking, hypertension and myocardial infarction.