Table 2.

Gene-set enrichment results for visceral asymmetry-related gene-sets, based on the UK Biobank GWAS for left-handedness versus non-left-handedness

mouse ID	Description	Pascal sum P	Pascal max P	Magma sum P	Magma max P	Magenta P
MP:0000508	right-sided isomerism	0.65	0.83	0.98	0.46	0.006a
MP:0000531	right pulmonary isomerism	0.64	0.68	0.97	0.76	0.06
MP:0000542	left-sided isomerism	0.77	0.59	0.52	0.73	0.10
MP:0000644	Dextrocardia	0.68	0.87	0.85	0.84	0.23
MP:0001706	abnormal left-right axis patterning	0.93	0.84	0.67	0.93	0.41
MP:0002766	situs inversus	0.40	0.51	0.70	1.00	0.49
MP:0003178	left pulmonary isomerism	0.70	0.52	0.55	0.90	0.13
MP:0004133	Heterotaxia	0.80	0.89	0.16	0.99	0.35
MP:0010808	right-sided stomach	0.34	0.72	0.86	0.95	0.17
MP:0011250	abdominal situs ambiguus	0.08	0.62	0.70	0.94	0.31
MP:0011252	situs inversus totalis	0.23	0.67	0.71	0.99	0.44
PCD	human primary ciliary dyskinesia	0.33	0.31	0.84	0.70	0.30

Notes: Different softwares and settings were used. See Supplementary Table 1 for the settings. The uncorrected P values for each gene-set and enrichment analysis are shown. ^aFDR = 0.035.