. 2018 Oct 29;122(5):622–635. doi: 10.1038/s41437-018-0161-3

Table 3.

Number of non-synonymous (NS) and synonymous (S) substitutions (D) and polymorphisms (P) and test statistics of McDonald–Kreitman (MK) test

Dataset	Chr	D			P			NI^a	MK-test p-value	DoS^b	DoS p-value
Dataset	Chr	NS	S	% NS	NS	S	% NS	NI^a	MK-test p-value	DoS^b	DoS p-value
LL vs. LM	A	27	73	27.00	808	2746	22.73	0.796	0.378	0.043	0.178
	LA	23	55	29.49	703	2069	25.36	0.813	0.488	0.041	0.217
	Z	3	20	13.04	55	132	29.41	2.778	0.159	−0.164	0.028
LL	A	300	933	24.33	588	1846	24.16	0.991	0.940	0.002	0.457
	LA	249	741	25.15	489	1493	24.67	0.975	0.810	0.005	0.386
	Z	23	102	18.40	36	118	23.38	1.353	0.387	−0.05	0.145
LM	A	380	1217	23.79	532	1531	25.79	1.113	0.179	−0.02	0.085
	LA	314	965	24.55	443	1225	26.56	1.111	0.232	−0.02	0.106
	Z	28	142	16.47	38	73	34.23	2.640	0.001	−0.178	0.000

LM vs. LL is for comparison between L. megarhynchos and L. luscinia, LM and LL states for lineage-specific test for L. megarhynchos and L. luscinia lineage, respectively. Significant p-values are indicated in bold

^aNeutrality index

^bDirection of selection