Fig. 5.

A representative example showing the differences of specific protein pairs in the DNA-PK-Ku-eIF2-NF90-NF45 protein complex across the three sample groups. a Scatter plots showing the log₂-transformed relative abundance ratios of XRCC6 plotted against those of XRCC5 (upper panel) as well as the log₂-transformed relative abundance ratios of ILF2 plotted against those of XRCC5 (lower panel) in the normal prostate, low-grade PCa, and high-grade PCa groups (from left to right). b Heatmap of z scores of all protein pairs (excluding self-pairs) within the DNA-PK-Ku-eIF2-NF90-NF45 protein complex. The abbreviations N, LG, and HG stand for normal prostate, low-grade PCa, and high-grade PCa, respectively