Table 3.
Detection, identification and quantification of contamination on the optimization set
| Dilutions | Expected contamination percentage | WCS contamination percentage | Refined contamination percentage | Contaminant | p-Value |
|---|---|---|---|---|---|
| A1 | 50% | 46.46% | 45.49% | Contaminant_1 | 3.12E−12 |
| A2 | 25% | 34.29% | 23.21% | Contaminant_1 | 4.17E−18 |
| A3 | 12.50% | 20.87% | 11.55% | Contaminant_1 | 2.00E−18 |
| A4 | 6.25% | 11.65% | 5.77% | Contaminant_1 | 1.32E−18 |
| A5 | 3.13% | 5.03% | 2.98% | Contaminant_1 | 3.57E−20 |
| B1 | 50% | 49.37% | 48.43% | Contaminant_2 | 1.05E−05 |
| B2 | 25% | 27.42% | 24.60% | Contaminant_2 | 9.30E–20 |
| B3 | 12.50% | 23.68% | 12.59% | Contaminant_2 | 1.56E–22 |
| B4 | 6.25% | 10.95% | 7.30% | Contaminant_2 | 3.57E–21 |
| B5 | 3.13% | 4.92% | 3.36% | Contaminant_2 | 1.83E–20 |
WCS worst-case scenario