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. 2018 Apr 5;16(4):401–409. doi: 10.1038/s41423-018-0026-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Low-dose DAC decreased the methylation level of the promoter region in tumors in the PDX model. a The violin map shows the methylation levels of the control and DAC-treated tumors. b Comparison of the methylation level of representative differentially expressed genes in the control and the DAC-treated tumors