Fig. 1.

a APLNR mRNA expression in normal renal tissue and in clear-cell renal cell carcinoma (ccRCC) tumour tissue (patients with localised and advanced disease). b APLN mRNA expression in normal renal tissue and in ccRCC tumour tissue (patients with localised and advanced disease). c Association between APLNR mRNA expression and histological grade of the tumour, ccRCC: lower expression in higher grade tumours (p = 0.027). d Association between APLNR mRNA expression and pT-stage of the tumour, ccRCC: lower expression in higher stage tumours (p = 0.009). For all plots: horizontal red line and associated value implies median of the expression in group