Fig. 5.

Clinical outcome of SHON protein nuclear and cytoplasmic expression in the chemotherapy-treated patients. Kaplan–Meier plots of the rates of distant metastasis-free survival (years) in the NUH-LABC cohort (n = 117), who received neoadjuvant anthracycline-based combination chemotherapy and if ERα⁺, followed by 5-year adjuvant tamoxifen, according to the status of SHON protein nuclear expression (SHON-Nuc) (a) and SHON protein cytoplasmic expression (SHON-Cyto) (b). The p value from the log rank test is shown in each panel; ‘n' is the number of samples in each group. + positive expression, − negative expression