a, b The effects of CZ-7 on 8-OHdG changes in hippocampal CA1 and CA3 region induced by chronic cerebral hypoperfusion in rats. Representative micrographs: ×200 magnification, scale bar = 100 μm. c Quantification analysis of CZ-7 on 8-OHdG-positive cells. Values are expressed as mean ± SEM. n = 3. ##P < 0.01 vs. Sham group, *P < 0.05, **P < 0.01 vs. Model group. For CA1, one-way ANOVA, F (5, 17) = 8.424,P = 0.0013. For CA3, one-way ANOVA, F (5, 17) = 4.667, P = 0.0134