Colocalization of Nrf2 and Iba-1, GFAP or MAP2 in the rat hippocampus by immunofluorescence. a, b The effects of CZ-7 on the levels of Nrf2 in hippocampus CA1 and CA3 region of rats based on double immunofluorescence assay with Iba-1. c, d The effects of CZ-7 on the levels of Nrf2 in hippocampus CA1 and CA3 region of rats based on double immunofluorescence assay with GFAP. e, f The effects of CZ-7 on the levels of Nrf2 in hippocampus CA1 and CA3 region of rats based on double immunofluorescence assay with MAP2. Representative micrographs: ×200 magnification, scale bar = 100 μm. The white arrows indicate the Nrf2 translocation from the cytoplasm to the nucleus