Fig. 2.

Role of HAI-2 in lung cancer cell motility. a Effect of HAI-2 knockdown on A549 lung cell migration and invasion. b Effect of HAI-2 silencing on CL1-0 cell migration and invasion. c Effect of HAI-2 overexpression on CL1-5 cell migration and invasion. CL1-5 cells were stably transfected with HAI-2.Myc construct for cell invasion and migration assays. The cells penetrating the transwells were counted and statistically calculated with a ratio to control cells (mean ± S.D., n = 3; *p < 0.05; **p < 0.005; ***p < 0.001). Magnification, x100