Table 1.
Descriptive characteristics of cancer cases in UKBB that were included in this study
| Cancer type | ICD-10 | Cancer diagnosis | Cancer mortality | ||||
|---|---|---|---|---|---|---|---|
| Females | Males | Total | Females | Males | Total | ||
| Stomach and oesophageal | C15/16 | 288 | 749 | 1037 | 136 | 414 | 550 |
| Colorectal | C18/20/21 | 1974 | 2571 | 4545 | 327 | 507 | 834 |
| Pancreatic | C25 | 248 | 294 | 542 | 199 | 248 | 447 |
| Lung | C34 | 971 | 1087 | 2058 | 597 | 731 | 1328 |
| Melanoma | C43 | 1748 | 1323 | 3071 | 71 | 111 | 182 |
| Breast | C50 | 11,703 | - | 11,703 | 768 | - | 768 |
| Endometrial | C53/54 | 1938 | - | 1938 | 143 | - | 143 |
| Ovarian | C56 | 1031 | - | 1031 | 270 | - | 270 |
| Prostate | C61 | - | 7532 | 7532 | - | 543 | 543 |
| Kidney | C64 | 379 | 689 | 1068 | 65 | 163 | 228 |
| Lymphoid | C81-96 | 1556 | 2102 | 3658 | 248 | 431 | 679 |
| Overall cancer | 24,989 | 21,166 | 46,155 | 3164 | 3834 | 6998 | |
Sample size listed here are already trimmed for genetic relatedness. The sum of the number of participants for each cancer type reported in this table does not add up to the number of the overall cancer cases since this table only shows the cancer types that were included in the cancer-specific analyses. In addition, the overall cancer set captures a smaller set of participants than the sum of the individual cancers due to two reasons: (1) people with multiple cancer incidence are only presented once (for the earliest cancer diagnosed) in the overall cancer set, and (2) combining all cancer sets requires the related people between the individual cancer sets to be removed
UKBB UK Biobank, ICD-10 International Statistical Classification of Diseases and Related Health Problems 10th Revision