Figure 2. Island fox genomes contain high proportions of amino acid-changing mutations and low neutral diversity.

A negative relationship exists between neutral genetic diversity (proxy for effective population size) and the ratio of heterozygosity at zero-fold relative to four-fold degenerate sites (proxy for efficacy of selection). Solid black lines connect individuals from the same population. Inset: The relationship holds even when removing San Nicolas. See also Figure S2, Table S4.