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A 75-year-old man with PSA 10.23 ng/mL with no prior biopsy history. Axial T2W MRI (A) shows a hypointense lesion in the midline apical peripheral zone, which shows restricted diffusion on ADC map (B) and b2000 DW MRI (C) (arrows). The lesion shows positive enhancement on DCE MRI (D) (arrow). The lesion was found to have Gleason 8(4 + 4) prostate adenocarcinoma on targeted biopsy.
