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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Urology. 2018 Jul 7;120:96–102. doi: 10.1016/j.urology.2018.06.037

Table 1.

Test characteristics of algorithms when applied to men with matched data in Michigan Medicare claims and MUSIC clinical registry. Bolded algorithms were selected to describe active surveillance trends in a national Medicare sample.

Algorithm Description Sensitivity Specificity PPV NPV
1 No treatment within 12 months of diagnosis 88.24 93.48 73.77 97.45
2 No treatment and 1 PSA within 12 months of diagnosis 84.31 93.69 73.50 96.64
3 No treatment and comorbidity score < 3 83.82 94.09 74.67 96.55
4 No treatment and comorbidity score < 2 77.45 94.60 74.88 95.28
5 No treatment and age < 75 65.20 96.33 78.70 93.02
6 No treatment within 12 months, comorbidity score < 3, and age < 75 62.25 96.54 78.88 92.49
7 No treatment, age < 75, and 1 PSA within 12 months of diagnosis 61.76 96.44 78.26 92.39
8 No treatment and ≥1 prostate biopsy between 1 and 12 months after diagnosis 23.53 99.08 84.21 86.18