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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Cancer Res. 2019 Jan 24;79(7):1343–1352. doi: 10.1158/0008-5472.CAN-18-2168

Figure 4.

Figure 4

Coomassie staining reveals the spatial heterogeneity of protein concentration in tumours. A. Examples of Coomassie stained tissue sections through a tumour of a representative rat. B-D. Magnified (200x) regions of tumour rim, tumour core and contralateral tissue, respectively. Group-wise protein concentration measurements (E) show that tumour rim has a significantly higher protein concentration than contralateral tissue, whereas tumour core has significantly lower protein concentration than contralateral tissue. **** = P < 0.0001, * = P < 0.05 (one-way repeated measures ANOVA, followed by Tukey’s multiple comparison test).