Table 1.
Average glomerular surface area and number of glomeruli in TG control and ETB-deficient rats after 3 weeks of high salt diet and daily treatment with vehicle or TUDCA. n = 6/group.
| GLOMERULAR SURFACE AREA (μm2) | |||
| TG control + 8% NaCl | ETB-deficient + 8% NaCl | ||
| Vehicle | TUDCA | Vehicle | TUDCA |
| 7761.7 ± 271.6 | 7167.2 ± 204.2 | 7782.2 ± 294.1 | 7254.1 ± 182.4 |
| NUMBER OF GLOMERULI (in 20 microscopy fields) | |||
| TG control + 8% NaCl | ETB-deficient + 8% NaCl | ||
| Vehicle | TUDCA | Vehicle | TUDCA |
| 83.0 ± 2.3 | 88.3 ± 2.9 | 98.0 ± 8.2 | 101.3 ± 5.8 |