. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Acta Physiol (Oxf). 2018 Dec 23;226(1):e13227. doi: 10.1111/apha.13227

Table 2.

Average numbers of T cells (CD3⁺ cells) and macrophages (ED-1⁺ cells) in renal cortex and outer and inner medulla of TG control and ET_B-deficient rats after 3 weeks of high salt diet and daily treatment with vehicle or TUDCA. n = 6/group. *P < 0.05 vs. same genotype + vehicle; ^†P < 0.05 vs. TG control + vehicle

CORTEX
	TG control + 8% NaCl		ET_B-deficient + 8% NaCl
	Vehicle	TUDCA	Vehicle	TUDCA
CD3⁺ cells (cells/field)	10.8 ± 0.5	9.1 ± 1.2	17.4 ± 4.5^†	10.8 ± 0.5*
ED-1⁺ cells (cells/field)	6.9 ± 0.7	7.1 ± 1.2	10.5 ± 2.2	6.8 ± 0.6
OUTER MEDULLA
	TG control + 8% NaCl		ET_B-deficient + 8% NaCl
	Vehicle	TUDCA	Vehicle	TUDCA
CD3⁺ cells (cells/field)	13.9 ± 1.1	9.1 ± 1.1*	14.0 ± 0.6	9.6 ± 0.8*
ED-1⁺ cells (cells/field)	4.1 ± 0.6	2.8 ± 0.7	4.0 ± 0.9	3.6 ± 0.5
INNER MEDULLA
	TG control + 8% NaCl		ET_B-deficient + 8% NaCl
	Vehicle	TUDCA	Vehicle	TUDCA
CD3⁺ cells (cells/field)	9.8 ± 4.8	10.9 ± 3.7	10.5 ± 3.2	5.6 ± 1.6
ED-1⁺ cells (cells/field)	2.4 ± 0.5	1.7 ± 0.5	2.4 ± 0.7	2.3 ± 0.5