Table 1.
Demographic and biological characteristics of the three groups: HIV positive and ART naive, HIV positive and ART-treated, and HIV negative
| HIV positive, ART naïve n=32 | HIV positive, ART treated n=52 | HIV negative n=72 | P | |
|---|---|---|---|---|
| Age in years, median (IQR) | 36(30-44) | 45(40-52) | 41(30-53) | 0.001 |
| Female, n(%) | 20(63) | 35(67) | 39(54) | 0.35 |
| BMI, (median IQR) | 22(20-23) | 23(21-27) | 21(20-25) | 0.08 |
| Gastric pH, Median (IQR) | 4.8(2.0-6.0) | 5.5(2.0-6.0) | 1.5(1.0-4.4) | <0.001 |
| Hypochlorhydria, n(%) | 19(59) | 29(56) | 18(25) | <0.001 |
| PG 1, Median (IQR) | 73.1(55.8-110) | 69.7(45.2-104.1) | 80.7(53.2-107.3) | 0.15 |
| *Low PG 1, μg/L, n(%) | 3(10) | 4(8) | 2(3) | 0.21 |
| PG 2, μg/L Median (IQR) | 14.7(9.8-38.6) | 12.7(6.9-20.7) | 14.0(9.9-22.0) | 0.25 |
| PG 1:2 ratio, Median (IQR) | 4.3(2.2-9.1) | 5.4(4.2-6.9) | 5.9(4.3-7.7) | 0.36 |
| **Low PG 1:2 ratio, n(%) | 10(37) | 4(7.6) | 6(8) | 0.001 |
| Gastrin-17 μg/L, Median (IQR) | 10.4(4.9-14.4) | 6.0(3.6-14.7) | *** | 0.08 |
| Low gastrin-17, n(%) | 1(3) | 5(10) | *** | 0.40 |
| H.pylori IgG antibody EIU, Median (IQR) | 61.4(38.2-86) | 76.4(38.2-99.1) | *** | 0.12 |
| H.pylori positive | 26(81) | 41(79) | *** | 0.10 |
*
Using 30 μg/L as the cut-off
**
Using 3.0 as the cut-off
****
In the previous study, gastrin-17 and H.pylori IgG antibodies were not measured