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. 2019 Apr 10;39(15):2965–2975. doi: 10.1523/JNEUROSCI.1728-18.2018

Table 1.

Intrinsic properties of FSIs and SPNs in Sapap3-KOs and WT littermatesa

Median, IQR FSIs
SPNs
WT KO p WT KO p
N (animals, cells) 5, 18 3, 25 4, 14 4, 25
Resting potential (mV) −76.03, 9.03 −81.17, 9.33 0.08 −82.98, 13.67 −86.18, 7.58 0.33
Rheobase (pA) 250, 150 300, 150 0.79 325, 150 225, 100 0.14
Maximum firing rate (Hz) 209, 124 250, 96 0.82 50, 9.50 44, 22 0.39
I-O curve linear slope 0.64, 0.64 0.56, 0.64 0.87 0.17, 0.11 0.22, 0.18 0.31
Input resistance (mΩ) 159.12,70.72 184.61, 108.91 0.12 299.80, 162.38 298.28, 120.76 0.70

aWT and KO groups were compared using WRST. No significant differences were observed.