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Antigenicity of BG505 SOSIP.664 disulfide mutant trimers
The binding of bNAbs, gl-bNAbs, and non-NAbs to PGT145-purified SOSIP.664 and mutant trimers was assessed by D7324-capture ELISA (Fig. 4). The AUC values are measures of binding efficiency. The fold changes in AUC value compared to SOSIP.664 for both mutants are listed, with those ≥1.5 highlighted in green.
