Magnetic resonance images of patient 1. Severe stenoses are located in the bilateral internal carotid arteries (green arrows), an acute infarct in the left corona radiates on diffusion-weighted images, and a subcortical arteriosclerotic encephalopathy is seen on the fluid-attenuated inversion recovery image (red arrow). In the regional cerebral blood flow map acquired by the pseudo-continuous labeling scan, lower perfusion was observed in the entire cerebral region, agreeing with the arterial flow rate result obtained using Non-Invasive Optimal Vessel Analysis. (This patient suffered from an emergency condition, and further surgery was necessary).