Figure 4.
Tumor growth and VEGF analysis of Avastin-treated group and control group. (A) Avastin inhibits MDA-MB-231HM tumor growth. Treatment with saline control (n=12) or Avastin (n=12), was initiated in established tumors (100 mm3) on day 8 post tumor cell injection and continued for three weeks. Tumor volume was measured once a week. Points, mean tumor volume; ***, P<0.0001, treatment versus control. (B) Measurement of the amounts of VEGF in the mice serum by ELISA. The level of VEGF was significantly lower in the serum from Avastin-treated group when compared to the control group. *, P<0.05 versus control. VEGF, vascular endothelial growth factor.