Table 1. Factors associated with ORR and OS.

ORR			OS
Univariate analysis	Multivariate analysis		Univariate analysis	Multivariate analysis
Normal LDH	Normal LDH		Normal LDH	Normal LDH
Stage M0, M1a, M1b			Stage M0, M1a, M1b
BTS below the median			BTS below the median	BTS below the median
Site of metastases	Site of metastases		Site of metastases	Site of metastases
PD-L1-positive tumors			PD-L1-positive tumors
No prior therapy	No prior therapy		No prior therapy
No prior ipilimumab treatment			ECOG performance status 0	ECOG performance status 0
Wild-type BRAF

ORR, overall rate of response; OS, overall survival; LDH, lactate dehydrogenase; BTS, baseline tumor size.