Figure 4.

Changes of IL-10-expression in the CD4⁺CD25⁺ and CD4⁺CD25^– T subsets of SLE patients after stimulation in comparison with healthy controls. IL-10-expression was determined by flow cytometry for intracellular cytokine analysis (*, P<0.05). Compared with healthy controls, SLE patients had an increased percentage of CD25⁺IL-10⁺ cells in CD4⁺ T cells, regardless of stimulation presence (A,B), while decreased TGF-β⁺ cells in the CD4⁺CD25^– T subset after stimulation, both in the percentage and in number (C,D).