Principles |
Ventilate the lug after clamping or cutting the target bronchus |
Inflate the segment through the target bronchus by bronchoscopic jet ventilation or direct intubation |
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Intravenously inject ICG after clamping or cutting the target pulmonary artery (target segment does not fluoresce) |
Stain the segment through the target bronchus by dye injection through a bronchoscope or directly through the endotracheal tube |
Multiple dye marks made at the corner of the target segment or adjacent segment, or beyond the segment, to obtain resection margins |
Timing |
Intraoperative |
Intraoperative |
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Intraoperative |
Preoperative/intraoperative |
Preoperative |
Advantages |
Very easy and quick |
Relatively easy |
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Easy and quick |
Dye remains longer than with intravenous injection (lasts the duration of the operation) |
Preoperative confirmation made regarding the relationship between the dye marks and the tumor, to secure margins (reproducibility) |
No preparation is needed |
Less interference with thoracoscopic view |
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Repeatable (fluorescence remains for a few minutes) |
May not need infrared thoracoscopy (fluorescence) |
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May help to obtain better resection margins |
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Demark the lung parenchyma around the hilum |
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Disadvantages |
Interferes with thoracoscopic view |
Some preparation needed |
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Collateral circulation and emphysematous lung may be misleading |
Airway secretions and collateral ventilation may obscure intersegmental lines |
Requires preoperative preparation |
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Needle-mediated injection is prohibited |
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Correct identification of pulmonary artery is mandatory |
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Requires basic instruments and an available facility (e.g., with fluoroscopy) |
Does not demark true intersegmental planes |
Intersegmental lines could be obscured because of collateral ventilation or airway secretions |
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Infrared thoracoscopy is required |
– |
Once electrocautery is used to develop the intersegmental planes, the inflated lung deflates and demarcation is obscured |
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