Table 6.
Current estimates of the seroprevalence of AAV 5 and AAV 8
| Authors | Region | n | Population | AAV 5 antibodies (%) | AAV 8 antibodies (%) | AAV 5 neutralizing factors (%) | AAV 8 neutralizing factors (%) |
|---|---|---|---|---|---|---|---|
| Boutin et al21 | France | 226 | Healthy adults | 40 | 38 | 3.2 | 19 |
| Calcedo et al44 | Australia, Europe, Africa, USA, | 100 | Healthy adults | — | 5‐32 | — | — |
| Liu et al45 | China | 500 | Healthy children and adults | 40.2 | 82 | — | — |
| Liu et al45 | China | 270 | HIV‐1 infected | — | — | 37 | — |
| Li et al26, 43 | Thailand, USA | 62 | Paediatric hemophilia A | 25.8 | 22.6 | — | — |
| Mimuro et al47 | Japan | 85 | Healthy adults | 37.6 | 32.9 | — | — |
| Mimuro et al47 | Japan | 59 | Hemophilia | 35.6 | 32.9 | — | — |
| Falese et al20 | USA | 100 | Healthy adults | 5 | — | 24 | — |
| Falese et al20 | USA | 24 | Hemophilia A | 8 | — | 8 | — |