Figure 2.

Confocal Microscopy Analysis of Aptamer Signals in Porcine Carotid from the 2-h Experiment

(A) Representative confocal images: Aptamers are visualized in blue, smooth muscle in red (phalloidin-Alexa Fluor 568), elastic fiber (auto-fluorescence) in green. High magnifications of boxed areas in panels in the left column are shown to the right side of each panel. Arrows indicate areas of prominent aptamer fluorescence. Scale bars, 1 mm for panels in the left column, 25 μm for panels in the right column. (B) Bar graph (with SE bars) showing normalized signal intensity in the wall of artery within 150 μm (the maximal signal depth of all) for each treatment. (C) Bar graph (with SE bars) representing signal depth of each treatment.