Table 2.
Summary of results from fixel-based analysis. All significant results are bilateral, unless the hemisphere is stated explicitly.
| Variable of interest | FD | FC | FDC |
|---|---|---|---|
| PMA (positive correlation) | Forceps minor | Body of corpus callosum | Body of corpus callosum |
| Forceps major | Corticospinal tract | Lateral projections of corpus callosum | |
| Lateral projections of the corpus callosum | Inferior longitudinal fasciculus | Forceps minor | |
| Corona radiata | Cerebellum | Forceps major | |
| Inferior fronto-occipital fasciculus | Corticospinal tract | ||
| Superior longitudinal fasciculus | Inferior fronto-occipital fasciculus | ||
| Inferior longitudinal fasciculus | Superior longitudinal fasciculus | ||
| Inferior longitudinal fasciculus | |||
| Thalamic regions | |||
| Cerebellum | |||
| GA at birth (corrected for PMA; positive correlation) | splenium of corpus callosum | Genu of corpus callosum | Genu of corpus callosum |
| tapetum of corpus callosum | Splenium of corpus callosum | Splenium of corpus callosum | |
| Left inferior fronto-occipital fasciculus | Anterior commissure | Tapetum of corpus callosum | |
| Right corticospinal tract | Anterior commissure | ||
| Inferior fronto-occipital fasciculus | Inferior fronto-occipital fasciculus | ||
| Superior longitudinal fasciculus | Inferior longitudinal fasciculus | ||
| Inferior longitudinal fasciculus | Fornix | ||
| Left Cingulum | |||
| Fornix | |||
| Thalamic regions | |||
| Cerebellum | |||
| Pons | |||
| Days on ventilation (corrected for PMA and GA; negative correlation) | Cerebellum | Genu of corpus callosum | Corticospinal tract |
| Pons | Splenium of corpus callosum | Inferior longitudinal fasciculus | |
| Tapetum of corpus callosum | Right Fornix | ||
| Anterior commissure | Cerebellum | ||
| Corticospinal tract | Pons | ||
| Anterior limb of the internal capsule | |||
| Inferior fronto-occipital fasciculus | |||
| Inferior longitudinal fasciculus | |||
| Fornix | |||
| Thalamic regions | |||
| Cerebellum | |||
| Pons | |||
| Days on total parenteral nutrition (corrected for PMA and GA; negative correlation) | NS | Corticospinal tract | NS |
| External capsule | |||
| Cerebellum | |||
| Pons | |||
| Birth weight z score (corrected for PMA and GA; negative correlation) | NS | Splenium of corpus callosum | Splenium of corpus callosum |
| Corticospinal tract | Corticospinal tract | ||
| Superior longitudinal fasciculus | Inferior fronto-occipital fasciculus | ||
| Inferior longitudinal fasciculus | Inferior longitudinal fasciculus | ||
| Cingulum | Right Fornix | ||
| Fornix | |||
| Cerebellum | |||
| Pons | |||
| Sex differences (male > female) | NS | Splenium of corpus callosum | Corticospinal tract |
| Corticospinal tract | |||
| Inferior fronto-occipital fasciculus | |||
| Superior longitudinal fasciculus | |||
| Cingulum | |||
| Fornix | |||
| Inferior longitudinal fasciculus | |||
| Cerebellum | |||
| Sex differences (female > male) | NS | NS | NS |
NS = not significant.