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. 2018 Sep 13;31(2):97–104. doi: 10.1038/s41443-018-0075-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Immunohistochemical staining of vWF. a Control group. b Diabetic ED group. c Epalrestat-treated group. d Statistical chart of the vWF density among groups; the arrows indicate the endothelium of cavernosum expressing vWF. *P < 0.01 compared to the normal control group; ^#P < 0.05 compared to the diabetic group. DED diabetic group, Epal epalrestat-treated group, vWF von Willebrand factor. Scale bars = 100 μm