Table 3.

Cox proportional hazards regression for medication-related factors and time to readmission within 90 days.

	Unadjusted HRs (95% CIs)	Adjusted HRs (95% CIs)
Model 1
MAI	1.04 (1.01–1.08)	1.04 (1.01–1.08)
MRCI	1.18 (1.01–1.39)	1.23 (1.03–1.47)
Use of RAS blockers	0.57 (0.38–0.89)	0.52 (0.33–0.83)
Model 2
MAI	1.04 (1.01–1.08)	1.03 (0.99–1.08)
MRCI	1.18 (1.01–1.39)	1.16 (0.96–1.39)
Use of RAS blockers	0.57 (0.38–0.89)	0.49 (0.30–0.78)

Abbreviations: HRs, hazard ratios; MAI, Medication Appropriateness Index; MRCI, medication regimen complexity index; RAS, renin-angiotensin system. Model 1: Analyses adjusted for age, gender and Charlson’s Comorbidity Index. Model 2: Analyses adjusted for factors in Model 1 plus eGFR, prior admissions and discharge destination.