Figure 5.

The C-terminal DNA binding domain of E. coli GyrA induces supercoiling losses in the Salmonella chromosome. (A) The genetic map of the different gyrase species tested is shown at the top (B) In vivo resolution results are compared for WT Salmonella gyrase―red numbers; strains with an E. coli gyrA replacing the Salmonella allele―black numbers; and two chimeras containing the N-terminal E. coli GyrA fused to Salmonella β-propeller elements at two points marked by blue and purple lines beneath the map.