Table 1.

Doubling times of S. Typhimurium and E. coli strains with different gyrase subunits and chimeric gyrases containing GyrA fusions to whole CTD or 1/2 CDT domains of Salmonella gyrA.

Strain	GyrA	GyrB	Doubling Time (min) on LB 30 °C
S.Tm NH6303	S. Tm	S. Tm	40 ± 1
S. Tm NH6304	S. Tm	E. coli	43 ± 1
S.Tm NH6281	E. coli	S.Tm	43 ± 1
S.Tm NH6292	E. coli	E. coli	44 ±1
S.Tm NH6390	E. coli <1/2 CTD S.Tm>	S.Tm	40 ± 2
S.Tm NN6392	E. coli <CTD S.Tm>	S. Tm	40 ± 1
S.Tm NH6391	E. coli <CTD S.Tm>	E. coli	39 ± 1
E. coli NH1013	E. coli	E. coli	39 ± 1
E. coli NH6386	S. Tm	E. coli	60 ± 3
E. coli NH6451	S. Tm <CTD E. coli>	E. coli	41 ± 1
E. coli NH6453	S. Tm <32 aa E. coli Tail>	E. coli	37 ± 1