Table 5.
Serum cytokines levels of IL-4, IL-12, TNF-α and IFN-γ in mice.
| Group | IL-4 (pg/mL) | IL-12 (pg/mL) | TNF-α (pg/mL) | IFN-γ (pg/mL) |
|---|---|---|---|---|
| Normal | 67.32 ± 2.56 e | 733.25 ± 22.59 a | 163.58 ± 10.11 a | 155.12 ± 11.05 a |
| Control | 30.58 ± 2.29 a | 162.37 ± 12.15 d | 31.05 ± 2.32 d | 29.36 ± 4.32 d |
| LDSB | 42.12 ± 3.15 d | 255.36 ± 25.30 c | 78.20 ± 9.52 c | 55.21 ± 5.36 c |
| LF-CQPC08-L | 43.25 ± 3.08 b | 259.17 ± 31.02 c | 81.98 ± 8.35 c | 57.89 ± 8.36 c |
| LF-CQPC08-H | 55.29 ± 2.91 c | 452.84 ± 26.34 b | 118.05 ± 5.13 b | 105.28 ± 4.11 b |
Values presented are the mean ± standard deviation (N = 10/group). a–d Mean values with different letters in the same row are significantly different (p < 0.05) according to Duncan’s multiple-range test. LDSB: mice treated with 4NQO and Lactobacillus delbruechii subsp. bulgaricus (1.0 × 109 CFU/kg); LF-CQPC08-L: mice treated with 4NQO and Lactobacillus fermentum CQPC08 (1.0 × 108 CFU/kg); LF-CQPC08-H: mice treated with 4NQO and Lactobacillus fermentum CQPC08 (1.0 × 109 CFU/kg). IL-4: interleukin-4; IL-12: interleukin-12; TNF-α: tumor necrosis factor-α; IFN-γ: interferon-γ.