Table 7.
p53, p63, p73 and PTEN mRNA expression in tongue tissue of mice (relative to multiple of control group).
| Group | p53 | p63 | p73 | PTEN |
|---|---|---|---|---|
| Normal | 0.11 ± 0.02 d | 0.09 ± 0.03 d | 0.18 ± 0.02 d | 0.32 ± 0.03 d |
| Control | 1.00 ± 0.06 a | 1.00 ± 0.04 a | 1.00 ± 0.07 a | 1.00 ± 0.04 a |
| LDSB | 0.65 ± 0.04 b | 0.78 ± 0.04 b | 0.62 ± 0.05 b | 0.75 ± 0.03 b |
| LF-CQPC08-L | 0.63 ± 0.03 b | 0.75 ± 0.04 b | 0.59 ± 0.06 b | 0.67 ± 0.04 b |
| LF-CQPC08-H | 0.29 ± 0.03 c | 0.58 ± 0.03 c | 0.31 ± 0.05 c | 0.48 ± 0.04 c |
Values presented are the mean ± standard deviation (N = 10/group). a–d Mean values with different letters in the same row are significantly different (p < 0.05) according to Duncan’s multiple-range test. LDSB: mice treated with 4NQO and Lactobacillus delbruechii subsp. bulgaricus (1.0 × 109 CFU/kg); LF-CQPC08-L: mice treated with 4NQO and Lactobacillus fermentum CQPC08 (1.0 × 108 CFU/kg); LF-CQPC08-H: mice treated with 4NQO and Lactobacillus fermentum CQPC08 (1.0 × 109 CFU/kg).