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. 2019 Mar 24;8(3):408. doi: 10.3390/jcm8030408

Figure 6.

Figure 6

YM155 decreases viability and BIRC5 expression in HS-SY-II cells. (a) Cells were treated for 24 h with various concentrations of YM155 and then assayed for the conversion of MTT to formazan and correlated to cell viability. (b) Caspase 3/7 & 8 activity detection in response to YM155 treatment. Fold increases are normalized to control treated HS-SY-II cells. Error bars are SDM. (c) Normalized mean values for Birc5 expression. BIRC5 was normalized with GAPDH mRNA expression, bars represent the SEM, n = 4 (p = 0.0006).