Table 3.
Disease severity with regard to TREM-1 rs2234237 genotypes.
| All (n = 649) | AA/AT (n = 104) | TT (n = 545) | p-Value | |
|---|---|---|---|---|
| General | ||||
| SOFA | 7 ± 4 | 7 ± 4 | 7 ± 3 | 0.4717 |
| SOFA respiratory score | 2 ± 1 | 2 ± 1 | 2 ± 1 | 0.8800 |
| SOFA cardiovascular score | 2 ± 1 | 2 ± 1 | 2 ± 1 | 0.7582 |
| SOFA central nervous system score | 2 ± 1 | 2 ± 1 | 2 ± 1 | 0.1310 |
| SOFA renal score | 1 ± 1 | 1 ± 1 | 1 ± 1 | 0.8692 |
| SOFA coagulation score | 0 ± 1 | 0 ± 1 | 0 ± 1 | 0.2439 |
| SOFA hepatic score | 0 ± 1 | 0 ± 1 | 0 ± 1 | 0.8126 |
| Organ support free days | ||||
| Ventilation free days | 5 ± 5 | 4 ± 5 | 5 ± 5 | 0.8157 |
| Vasopressor free days | 10 ± 7 | 10 ± 7 | 10 ± 7 | 0.5074 |
| Dialysis free days | 14 ± 8 | 14 ± 8 | 14 ± 8 | 0.7018 |
| Ventilation free days/observation days (%) | 66 ± 32 | 65 ± 34 | 67 ± 31 | 0.9150 |
| Vasopressor free days/observation days (%) | 34 ± 30 | 34 ± 30 | 33 ± 30 | 0.7081 |
| Dialysis free days/observation days (%) | 9 ± 22 | 9 ± 22 | 10 ± 23 | 0.6751 |
| Inflammatory values: | ||||
| Leucocytes (1000/µL) | 13 ± 5 | 13 ± 5 | 13 ± 5 | 0.4353 |
| CRP (mg/L) | 151 ± 87 | 164 ± 89 | 148 ± 86 | 0.1946 |
| Procalcitonin (ng/dL) | 4 ± 9 | 5 ± 13 | 4 ± 8 | 0.9562 |
| Kidney values | ||||
| Urine output (ml/day) | 2980 ± 1333 | 2864 ± 1280 | 3002 ± 1343 | 0.2934 |
| Urine output (ml/kg/h) | 2 ± 1 | 2 ± 1 | 2 ± 1 | 0.7470 |
| Creatinine (mg/dL) | 1.2 ± 1 | 1.2 ± 0.8 | 1.2 ± 1 | 0.7346 |
| Liver values | ||||
| AST (GOT) (IU/L) | 168 ± 595 | 114 ± 229 | 177 ± 642 | 0.3071 |
| ALT (GPT) (IU/L) | 93 ± 188 | 74 ± 142 | 97 ± 195 | 0.0630 |
| Bilirubin (mg/dL) | 1.2 ± 2 | 1.1 ± 1.7 | 1.2 ±2 | 0.9725 |
| Central nervous system | ||||
| GCS | 10 ± 3 | 10 ± 3 | 10 ± 3 | 0.1553 |
| Coagulation: | ||||
| Thrombocytes (1000/µL) | 296 ± 152 | 274 ± 131 | 300 ± 155 | 0.1810 |
Footnote: SOFA, sequential organ failure assessment; CRP, C-reactive protein; GCS, Glasgow Coma Scale; AST, aspartate amino transferase; GOT, glutamic oxalo acetic transaminase; ALT, alanine aminotransferase; GPT, glutamic-pyruvic transaminase.