Table 1.
Examples of successfully repositioned drugs.
| Drug | Original indication | Reposition |
|---|---|---|
| Amantadine | Influenza | Parkinson’s disease |
| Amphotericin | Antifungal | Leishmaniasis |
| Aspirin | Inflammation, pain | Antiplatelet |
| Bromocriptine | Parkinson’s disease | Diabetes mellitus |
| Bupropion | Depression | Smoking cessation |
| Colchicine | Gout | Recurrent pericarditis |
| Finasteride | Benign prostatic hyperplasia | Male pattern baldness |
| Gabapentin | Epilepsy | Neuropathic pain |
| Methotrexate | Cancer | Psoriasis, rheumatoid arthritis |
| Miltefosine | Cancer | Visceral leishmaniasis |
| Minoxidil | Hypertension | Male pattern baldness |
| Propranolol | Hypertension | Migraine prophylaxis |
| Sildenafil | Angina | Erectile dysfunction, pulmonary hypertension |
| Thalidomide | Morning sickness | Erythema nodosum leprosum |
| Zidovudine | Cancer | HIV/AIDS |