Figure 7.

In vivo bacterial counts after lung infections with MRSA-L by nose inoculation of bacteria. Pneumonia was established in C75BL/6 mice (n = 5 in each group) by inoculating with (A) MRSA/JD004 or (B) MRSA/JD004-T1 through the nose. Three doses of 400 mg/kg oxacillin were intraperitoneally injected after infection. No bacteria could be recovered from lung homogenized fluid from mice infected with MRSA/JD004-T1. (C) Statistical data pooled from all mice. N.D.: none detectable, *** p = 0.0004, paired Student t-test.