Table 1.
Characteristics of healthy volunteers, standard care patients with bacterial infections, and intensive care patients.
| Parameter | HC | SC | ICU | ICU: No Sepsis | ICU: Sepsis |
|---|---|---|---|---|---|
| Number n | 63 | 50 | 105 | 53 | 52 |
| Sex (male/female) n | 37/26 | 33/17 | 66/39 | 35/18 | 31/21 |
| Age (years) | 48 (22–77) | 66.5 (21–90) | 66 (18–97) | 60 (23–92) | 68 (18–97) |
| RBC (per nL) | 4.8 (4.2–6.7) | 4.15 (2.2–6.2) | 3.5 (2–9.4) | 3.7 (2–6.3) | 3.4 (2.1–9.4) |
| Hemoglobin (g/dL) | 14.1 (12–16) | 12.5 (7.1–17.5) | 10.2 (5.6–16.1) | 10.8 (5.6–15.5) | 9.55 (6.2–16.1) |
| Hematocrit (%) | 41.4 (36.1–46.1) | 36.9 (23.7–51.3) | 30.9 (16.6–50.5) | 32 (16.6–50.5) | 29.8 (19.1–50.3) |
| WBC (per nL) | 5.8 (3.7–10) | 9.2 (1.7–23) | 13.5 (0.5–42.9) | 10.6 (2.7–31.4) | 15.4 (0.5–42.9) |
| Lymphocytes (per nL) | 1.86 (0.72–3.13) | 0.75 (0–3.46) | 0.64 (0–6.86) | 0.75 (0–3.46) | 0.53 (0.02–6.86) |
| B cells (per nL) | 0.13 (0.04–0.60) | 0.066 (0–0.55) | 0.088 (0–1.40) | 0.10 (0–0.66) | 0.064 (0–1.40) |
| T cells (per nL) | 1.34 (0.27–2.54) | 0.66 (0.09–2.67) | 0.43 (0–3.28) | 0.51 (0–2.09) | 0.34 (0.01–3.28) |
| NK cells (per nL) | 0.26 (0.08–0.78) | 0.11 (0.01–0.79) | 0.084 (0–2.59) | 0.10 (0–1.65) | 0.053 (0–2.59) |
The median and range are given, unless indicated otherwise. The two right columns differentiate the characteristics of ICU patients with or without sepsis. Abbreviations: WBC: white blood cell count, RBC: red blood cell count, HC: healthy control, SC: standard care patients, ICU: intensive care unit; NK cells: natural killer cells.