Table 2.
Multiple logistic regression analysis of different risk factors with Helicobacter pylori infection.
| Helicobacter pylori | |||
|---|---|---|---|
| OR | 95% C.I. | p | |
| Age | |||
| <40 years | 1 | ||
| ≥40 years | 0.73 | (0.33–1.62) | 0.44 |
| Gender | |||
| Male | 1 | ||
| Female | 0.7 | (0.37–1.32) | 0.02 |
| BMI category | |||
| Normal | 1 | ||
| Overweight and Obese | 1.49 | (0.82–2.72) | 0.19 |
| Education Level | |||
| Primary | 1 | ||
| School | 2.46 | (0.96–6.34) | 0.06 |
| University | 4.16 | (1.52–11.4) | 0.01 |
| Marital Status | |||
| Not Married | 1 | ||
| Married | 1.03 | (0.5–2.1) | 0.93 |
| Alcohol Consumption | |||
| No | 1 | ||
| Yes | 1.42 | (0.76–2.67) | 0.27 |
| Vitamin D status | |||
| Insufficiency | 1 | ||
| Deficiency | 0.03 | (0.01–0.06) | <1 × 10−3 |
| Normal | 0.01 | (0–0.02) | <1 × 10−3 |
| Gene SNPs | |||
| rs10004195 in TLR1 | 1.23 | (0.8–1.8) | 0.29 |
| rs10759932 in TLR4 | 1.37 | (0.75–2.48) | 0.30 |
| rs10983755 in TLR4 | 0.51 | (0.05–5.44) | 0.58 |
| rs11536889 in TLR4 | 1.51 | (0.82–2.79) | 0.19 |
| rs1898830 in TLR4 | 0.84 | (0.55–1.29) | 0.44 |
| rs4986790 in TLR4 | 7.09 | (1.12–45) | 0.04 |
| rs4986791 in TLR4 | 0.14 | (0.02–0.86) | 0.03 |
| rs2569190 in CD14 | 0.74 | (0.49–1.12) | 0.15 |
| rs760805 in RUNX3 | 0.78 | (0.53–1.15) | 0.21 |
Reference categories of gene single nucleotide polymorphisms were not shown since no significant association was found. C.I., confidence interval.