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. 2019 Mar 1;8(3):292. doi: 10.3390/jcm8030292

Figure 2.

Figure 2

The effects of anorexigenic neuropeptides PACAP (pituitary adenylate cyclase-activating polypeptide) and corticotropin-releasing factor (CRF) on oscillation in the ventromedial hypothalamus. (A,B) Examples of continuous recordings of ventromedial hypothalamus field potential before and after the application of 50 nM PACAP and 50 nM CRF, respectively. (A’,B’) Faster sweep representations: a and b correspond to records at “a” and “b” in (A,B), and after 20-min washout (wash). The frequency of the oscillation was increased by the application of each of the peptides. Note that the application of PACAP or CRF also increased background tonic activity. FP: raw field potential; ∫FP: integrated field potential; wash: washout.