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. 2019 Mar 5;7(3):70. doi: 10.3390/microorganisms7030070

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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MmpL transporters export substrates that are important for virulence and pathogenicity. MmpL proteins and membrane-associated transport partners, exported substrates, and contributions to virulence/pathogenicity of the mature exported substrates. TMM/TDM—trehalose mono/di-mycolate; AGP—arabinogalactan/peptidoglycan complex; (c)MBT—(carboxy)mycobactin; PDIM—phthiocerol dimycocerosate; PAMP—pathogen-associated molecular pattern; PRR—pattern recognition receptor; DAT/PAT—di/poly-acyl trehalose; LC-TAG—long-chain triacylglycerol; and MWE—mycolate wax ester.