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. 2019 Mar 12;8(3):346. doi: 10.3390/jcm8030346

Table 3.

Univariate and multivariate Cox analyses in the cohort of 149 patients with early-stage CRC.

Univariate OS Analysis Multivariate OS Cox Analysis
HR 95% CI p HR 95% CI p
Lower Upper Lower Upper
Age 0.319 -
<70 1.000
>70 1.352 0.747 to 2.445 - -
Stage 0.003 0.235
II 1.000 1.000
III 3.421 1.540 to 7.601 1.956 0.646 to 5.926
ECOG <0.001 <0.001
0–1 1.000 1.000
2–3 2.797 1.975 to 3.961 2.653 1.845 to 3.814
T 0.002 0.057
1–2 1.000 1.000
>2 1.785 1.226 to 2.599 1.488 0.989 to 2.240
N 0.001 0.275
0–1 1.000 1.000
2–x 1.599 1.223 to 2.091 1.263 0.830 to 1.921
SET 0.001 0.010
No 1.000 1.000
Yes 2.873 1.547 to 5.335 2.387 1.229 to 4.634

OS: overall survival; CI: confidence interval, and HR: hazard-ratio. Bold: p < 0.01.