Table 5.
Association between TNIP1 haplotypes and death in septic shock patients.
| TNIP1 Haplotypes | Association | |||||
|---|---|---|---|---|---|---|
| Exitus | rs73272842 | rs3792783 | rs7708392 | Freq. | aOR (95% CI) | p-Value |
| 28 days | G | A | G | 0.745 | 0.53 (0.30; 0.92) | 0.024 |
| A | G | C | 0.122 | 1.90 (0.96; 3.79) | 0.069 | |
| G | A | C | 0.111 | 1.59 (0.75; 3.37) | 0.227 | |
| 90 days | G | A | G | 0.745 | 0.62 (0.36; 1.05) | 0.071 |
| A | G | C | 0.122 | 2.09 (1.05; 4.17) | 0.031 | |
| G | A | C | 0.111 | 1.08 (0.53; 2.20) | 0.840 | |
Values are expressed as odds ratio and 95% confidence interval. p-values were calculated by multivariate logistic regression adjusted by the most important clinical and epidemiological characteristics. Only haplotypes with frequency >0.1 are shown. Significant differences are shown in bold. aOR adjusted odds ratio; 95% CI, 95% confidence interval; SNPs, single nucleotide polymorphisms; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells; TNIP1, TNFAIP3 (TNF alpha-induced protein 3) interacting protein 1.