Figure 6.

LINC01419 downregulation prevents ESCC progression and increases the sensitivity of ESCC cells to 5-FU in vivo. (a) the size of xenograft tumor in nude mice. Statistical values were measurement data, presented as mean ± standard deviation and compared by two-way analysis of variance. The experiment was repeated three times, n = 5, *p < 0.05, **p < 0.01, ***p < 0.001. (b) xenograft tumor diagram of nude mice in 28 day; (c) the weight of xenograft tumor in nude mice, n = 5. *p < 0.05, **p < 0.01, ***p < 0.001. The statistical values included measurement data, presented as mean ± standard deviation and compared with analysis of variance. The experiment was repeated three times.

5-FU, 5-fluorouracil; EdU, 5-ethynyl-2’-deoxyuridine; ESCC, esophageal squamous cell carcinoma.