Table 5.
Study | Study type | Sample size | Follow-up | Results and conclusions |
---|---|---|---|---|
Gomes et al.97 | Cohort study | n = 14 | 12-month minimum | Rotator cuffs repaired with BMSC injections at the repair borders showed MRI preservation in 14/14 (100%) cases at 12 months. UCLA shoulder scores significantly improved at 12 months and remained stable in 13/14 (93%) patients at 24 months. |
Hernigou et al.98 | Case–control study | n = 90 | 10 years | BMSC-treated repairs healed two months faster than controls via MRI and US evaluation. All treatment repairs fully healed at six months versus 30/45 (67%) in the control group. Long-term maintenance of tendon integrity of 39/45 (87%) in the treatment group versus 44% in the control group (p < 0.05). |
BMSC: bone marrow-derived mesenchymal stem cell; MRI: magnetic resonance imaging; UCLA: University of California at Los Angeles; US: ultrasound.