Ubel et al[12] |
1 |
Nil |
Embedment of follicular units inPRP solution before surgery |
Manual counting with magnifying glass |
15.1% better graft survival |
Greco and Brandt et al[13] |
1 |
Nil |
Injection and microneedling |
Hair diameter measures by Starret micrometer |
Increase in average hair shaft diameterAt 4 months: 9.7%At 8 months: 6.1% |
Kang et al[14] |
2 |
3 months |
Interfollicular injections of CD34+cell containing PRP of 0.05-0.1 ml/cm2 |
Digital imagesPhototrichogram |
Improvement in the mean number of hairs and in mean hair thickness, respectivelyAt 3 months: 20.5±17.0% and 31.3±30.1%At 6 months: 29.2±17.8% and 46.4±37.5% |
Betsi et al.[9] |
5 |
12 days |
Injections |
Clinical examDigital imagesHair pull testPatient’s satisfaction |
All patients after third treatment had negative hair pull test and an 25% decrease of hair lossPatients’ satisfaction: 7.0 on a scale of 1-10 |
|
Khatu et al[10] |
4 |
2 weeks |
Injections (nappage technique) |
Global photographsClinical examPhototrichogram(trichoscan)Patient’s assessment scale |
At 3 monthsNegative hair pull test in 81.81% of patientsModerate improvement in hair volume and coverageMean increase in hair density: 22.09 follicular units/cm2 |
Gkini et al[11] |
4 |
3 weeks and last session at 6 months |
Injections |
Macroscopic photographsClinical examHair pull testDermoscopicmicrophotographsPatient’s assessment scale |
Increase in hair density compared to that of baselineAt 3 months<0.001Negative hair pull testHair density: 170.70±37.81 (maximum value)At 6 months<0.001Hair density: 156.25±37.75At 1-year<0.001Hair density: 153.70±39.92Patients’ satisfaction: 7.1 on a scale of 1-10. |
Present study |
4 |
1 month |
Intradermal injections |
Global photographsHair pull testStandardized hair growth questionnairePatient satisfaction score |
On Global photography: Better outcome in PRP group as compared to minoxidil groupHair pull test negative in 75% in PRP compared to 42.8% in group B6.56±1.09 in PRP group v/s 4.85±1.46 (p-value: 0.001) |