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. 2019 Mar-Apr;11(2):68–79. doi: 10.4103/ijt.ijt_64_18

Table 15.

Treatment protocols, evaluation methods, and results of various studies in comparison to the present study for Group A (platelet-rich plasma group)

Study Sessions Interval between sessions Method of application Evaluation methods Results
Ubel et al[12] 1 Nil Embedment of follicular units inPRP solution before surgery Manual counting with magnifying glass 15.1% better graft survival
Greco and Brandt et al[13] 1 Nil Injection and microneedling Hair diameter measures by Starret micrometer Increase in average hair shaft diameterAt 4 months: 9.7%At 8 months: 6.1%
Kang et al[14] 2 3 months Interfollicular injections of CD34+cell containing PRP of 0.05-0.1 ml/cm2 Digital imagesPhototrichogram Improvement in the mean number of hairs and in mean hair thickness, respectivelyAt 3 months: 20.5±17.0% and 31.3±30.1%At 6 months: 29.2±17.8% and 46.4±37.5%
Betsi et al.[9] 5 12 days Injections Clinical examDigital imagesHair pull testPatient’s satisfaction All patients after third treatment had negative hair pull test and an 25% decrease of hair lossPatients’ satisfaction: 7.0 on a scale of 1-10

Khatu et al[10] 4 2 weeks Injections (nappage technique) Global photographsClinical examPhototrichogram(trichoscan)Patient’s assessment scale At 3 monthsNegative hair pull test in 81.81% of patientsModerate improvement in hair volume and coverageMean increase in hair density: 22.09 follicular units/cm2
Gkini et al[11] 4 3 weeks and last session at 6 months Injections Macroscopic photographsClinical examHair pull testDermoscopicmicrophotographsPatient’s assessment scale Increase in hair density compared to that of baselineAt 3 months<0.001Negative hair pull testHair density: 170.70±37.81 (maximum value)At 6 months<0.001Hair density: 156.25±37.75At 1-year<0.001Hair density: 153.70±39.92Patients’ satisfaction: 7.1 on a scale of 1-10.
Present study 4 1 month Intradermal injections Global photographsHair pull testStandardized hair growth questionnairePatient satisfaction score On Global photography: Better outcome in PRP group as compared to minoxidil groupHair pull test negative in 75% in PRP compared to 42.8% in group B6.56±1.09 in PRP group v/s 4.85±1.46 (p-value: 0.001)